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Published on: June 20, 2020
Persistent failure-to-thrive: a case study
1Riley Children's Hospital, Indiana University Medical Center, Indianapolis 46202-5210, USA.
Insights
Addressing infant feeding difficulties requires managing both physical and behavioral issues. This case study explores nonregurgitant gastroesophageal reflux and behavioral interventions for persistent failure-to-thrive.
Area of Science:
- Pediatrics
- Gastroenterology
- Developmental Psychology
Background:
- Infant feeding problems and growth failure cause significant parental and clinical concern.
- Early growth failures often indicate difficulties with infant homeostasis, requiring medical management of physical issues.
- Behavioral problems frequently accompany growth failure and necessitate integrated treatment approaches.
Observation:
- A case study involving a child with poor growth and respiratory symptoms due to nonregurgitant gastroesophageal reflux is presented.
- Nonregurgitant gastroesophageal reflux is a challenging clinical entity to diagnose.
- Surgical intervention for the reflux was successful, yet the child's failure-to-thrive persisted.
Findings:
- The study discusses the use of cyproheptadine as an appetite stimulant for persistent poor weight gain.
- A review of current literature on pharmacologic approaches to poor weight gain is included.
- A behavioral-based treatment plan is described as an alternative to pharmacologic interventions.
Implications:
- Recognizing and managing nonregurgitant gastroesophageal reflux is crucial for infant growth.
- Integrated medical and behavioral management is essential for addressing complex feeding and growth issues.
- Behavioral interventions offer a viable alternative to pharmacologic agents for promoting weight gain in challenging cases.
Abstract:
The inability to successfully feed a young infant or child is as worrisome to parents as it is to the health care provider. Early growth failures are likely to reflect difficulty with infant homeostasis and often respond to medical management of the physical problem that is temporarily interfering with the infant's ability to feed by mouth. In addition to medical management, however, treatment also necessitates investigation and management of behavioral problems that so universally accompany growth failure. This article presents a case study of a child who presented with poor growth and respiratory symptoms associated with nonregurgitant gastroesophageal reflux, a clinical entity that can be difficult to recognize. Although surgical management of this condition was successful, persistent failure-to-thrive continued and was seemingly recalcitrant to treatment. The use of cyproheptadine as an appetite stimulant to promote weight gain in this child is discussed with a review of the current literature regarding this pharmacologic approach to poor weight gain. A behavioral-based treatment plan is described as an alternate management method, avoiding the use of pharmacologic agents in general.
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