[Adenovirus typing and distribution in swine]

Adenoviruses isolated from pigs (RO-KL; SA3; RO; and R10) and the prototypic strain Compton 25R, belonging to the 1st serologic group, are responsible for the formation of intranuclear bodies of the Cowdry-A type, while the virus Ad5 strain (isolated from humans) cause the formation of another variant of nuclear inclusions of the Cowdry-B type known as Central mass. All virus strains propagate in primary cell cultures of pig kidney and calf and rabbit kidney, calf testis, and in the stable cell line PK-15, showing negligible variations. Resistance and stability experiments have demonstrated that the investigated strains posses physico-chemical and morphologic properties that are characteristic of the adenoviruses. The virus strain isolated in Bulgaria, and the strains isolated in Hungary can be classified in the IVth serologic group of swine adenoviruses. The study of serum samples taken in different regions of Bulgaria and Hungary in order to establish adenovirus antibodies have revealed that in about 20.5 per cent of the swine sera in Hungary, and in 19 per cent, on an average, of the sera taken in Bulgaria there are adenovirus antibodies.