An erythema multiforme-like eruption caused by exposure to 1-chloromethylnaphthalene

A young male patient developed an erythema multiforme-like eruption following an accidental exposure to 1-chloromethylnaphthalene (1-CMN). In addition to the skin lesion, he suffered from liver involvement and tear insufficiency. Positive results of a patch test with 1-CMN and an in vitro lymphocyte transformation test suggested that direct exposure of the skin to chemical compounds was the probable cause of his symptoms.