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Merkel cell carcinoma: report of three cases
O Okamoto1, M Yoshiyama, S Takayasu
1Department of Dermatology, Oita Medical University, Japan.
The Journal of Dermatology
|March 31, 1998
Abstract:
Three cases of Merkel cell carcinoma are reported: Case 1 on the upper eyelid with regional lymph node metastasis, Case 2 with spontaneous regression after repeated biopsies, and Case 3 presumably developing on the lesion of pre-existing Bowen's disease. In Case 2, the biopsy specimen was characterized by numerous apoptotic cells in the periphery of the tumor nests surrounded by lymphocytic infiltration. In Case 3, the tumor developed after injury to the pre-existing lesion of Bowen's disease.