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Related Experiment Videos

The evolution of 'bricolage'

D Duboule1, A S Wilkins

  • 1Department of Zoology and Animal Biology, University of Geneva, Switzerland. denis.duboule@zoo.unige.ch

Trends in Genetics : TIG
|April 1, 1998
PubMed
Summary
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Animal diversity arises from shared genes used differently across species. This functional interdependence influences variation tolerance, driving evolution through a

Area of Science:

  • Developmental genetics
  • Evolutionary biology
  • Comparative genomics

Background:

  • Most genes are conserved across the animal kingdom.
  • Animal diversity may stem from differential gene usage.

Purpose of the Study:

  • To explore how shared genes and their differential usage contribute to animal diversity.
  • To propose a 'transitionist' evolutionary model based on functional interdependence.

Main Methods:

  • Comparative analysis of gene usage across species.
  • Theoretical modeling of genetic networks and functional interdependence.
  • Review of developmental genetics findings.

Main Results:

  • Shared genetic components are recruited differently, leading to functional interdependence.

Related Experiment Videos

  • Increased interdependence limits the tolerance for novel variations.
  • Evolutionary complexity progresses through phases of gradualism and punctuation.

    • Conclusions:

    • Differential gene usage is a key driver of animal diversity.
    • Functional interdependence shapes the pace and pattern of evolution.
    • The 'transitionist' model reconciles gradual and punctuated evolutionary theories.