Assisted circulation for end-stage chronic heart failure

Area of Science:

• Cardiovascular Engineering
• Biomedical Devices
• Heart Failure Therapy

Background:

• Electromechanical left ventricular assist devices (LVADs) are prevalent, but pneumatic systems offer unique advantages.
• End-stage chronic heart failure necessitates advanced circulatory support solutions.
• The ProCor Model 1 represents a novel pneumatic LVAD system.

Purpose of the Study:

• To describe the design and functionality of the ProCor Model 1 pneumatic LVAD.
• To highlight its features for prolonged circulatory assistance in heart failure patients.
• To present its potential role as an alternative to existing LVAD technologies.

Main Methods:

• The ProCor Model 1 features a compact, double-pusher plate implantable pump and a small, portable power pack.
• The device synchronizes with the electrocardiogram (ECG) to pump during the diastolic period.
• A multipurpose pneumatic tube integrates ECG sensing and pacing capabilities, alongside a porcine bioprosthesis.

Main Results:

• The system is designed for constant driving conditions: 60 bpm rate, 25% systolic duration, 1,800 mm Hg/s dP/dt, and 250 mm Hg driving pressure.
• This configuration achieves a basic pump output of 3.500 L/min for sustained circulatory support.
• The integrated pneumatic tube allows for potential cardiac pacing if required.

Conclusions:

• The ProCor Model 1 pneumatic LVAD demonstrates potential for long-lasting, compact circulatory assistance.
• Its design incorporates advanced features for enhanced patient management and support.
• This pneumatic system offers a viable alternative in the treatment of end-stage chronic heart failure.