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[Bladder pseudosarcoma in pediatrics: clinico-pathological features and treatment]
J M Díez Rodríguez1, J Extramiana Cameno, M J Mora Durban
1Servicio de Urología, Hospital de Móstoles, Madrid, España.
Archivos Espanoles De Urologia
|April 4, 1998
Summary
Inflammatory pseudotumor of the bladder is a rare, benign condition in children. Long-term follow-up confirms its benign nature, supporting conservative management for this bladder tumor.
Area of Science:
- Pediatric Urology
- Pediatric Oncology
- Pathology
Background:
- Inflammatory pseudotumor of the bladder is an uncommon benign neoplasm.
- Distinguishing it from malignant bladder tumors in children is crucial for appropriate management.
Observation:
- This review analyzes 18 pediatric cases (16 from literature, 2 new) of inflammatory pseudotumor of the bladder.
- Common symptoms include hematuria, dysuria, and abdominal pain.
- Tumors ranged from 3-10 cm, often located in the lateral bladder walls or base.
Findings:
- Histological analysis revealed an inflammatory pseudosarcomatous reaction.
- Immunohistochemistry showed vimentin positivity and focal muscle actin positivity, with negative keratin and S-100.
- Treatment varied from local resection to radical cystectomy; 14/16 patients showed no recurrence after a mean 34-month follow-up.
Implications:
- Inflammatory pseudotumor of the bladder is a rare but benign entity in children.
- Conservative management is recommended due to the lesion's benign nature.
- Close follow-up is advised due to histological similarities with malignant neoplasms.