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Renal effects of renin-angiotensin system blockade
M Franco1, R Paniagua, J Herrera-Acosta
1Department of Nephrology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Current Opinion in Nephrology and Hypertension
|April 8, 1998
Abstract:
Pharmacological interruption of the renin-angiotensin system at different pathway levels has extended our knowledge on the distribution of angiotensin receptors in different nephron segments, its regulation and tubular cell responses. Novel beneficial effects obtained with blockade of this peptide on cellular proliferation and its interaction with other vasoactive systems are particularly important for preventing renal damage.