Perforated leiomyosarcoma of Meckel's diverticulum

Area of Science:

• Gastroenterology
• Surgical Oncology
• Pathology

Background:

• Meckel's diverticulum leiomyosarcoma is a rare malignancy.
• It is the most common tumor arising from Meckel's diverticulum.
• Clinical presentations typically include abdominal pain, bleeding, mass, or obstruction.

Observation:

• Two cases of perforated Meckel's diverticulum leiomyosarcoma are presented.
• Perforation is an uncommon presentation, occurring in only 4 of 59 reported cases.
• Both patients presented with perforation, an unusual clinical manifestation.

Findings:

• Despite late presentation with perforation, both tumors were resectable.
• Neither patient had evidence of distant or local metastasis post-resection.
• Both patients, aged 89 and 69, remained disease-free at 3 years and diagnosis respectively.

Implications:

• Surgical resection is feasible even in advanced presentations of Meckel's diverticulum leiomyosarcoma.
• Early diagnosis and prompt surgical intervention are crucial for favorable outcomes.
• This highlights the importance of considering leiomyosarcoma in Meckel's diverticulum, even with atypical symptoms like perforation.