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A novel DRB1*0801 haplotype carrying DRB3*0202 found in a German pedigree
D F Chen1, L T Pastucha, E D Albert
1Blutbank-Immunhämatologie-Transfusionsmedizin, Medizinische Hochschule Hannover, Germany.
Abstract:
DRB1*08 haplotypes have not been known to carry a DRB3 gene. We have found a patient suffering from liver disease who has a novel HLA haplotype of DRB1*0801 with DRB3*0202 as established by family segregation. These two genes were confirmed by sequencing. DR8 and DR52 antigen specificities were serologically detected, indicating expression of these genes.