Paediatric cycloplegia: a new approach

P Shah1, A S Jacks, G G Adams

  • 1Moorfields Eye Hospital, London, UK.

Eye (London, England)
|January 1, 1997
PubMed

Insights

Using proxymetacaine before cyclopentolate eye drops significantly reduces distress in children. This atraumatic approach improves the child

Area of Science:

  • Ophthalmology
  • Pediatric Care

Background:

  • Cycloplegia using cyclopentolate eye drops is often traumatic for children due to stinging.
  • This discomfort can lead to inadequate cycloplegia, examination difficulties, and patient anxiety.
  • Proxymetacaine hydrochloride 0.5% is a non-stinging topical anesthetic.

Purpose of the Study:

  • To evaluate the efficacy of proxymetacaine in preventing discomfort associated with cyclopentolate-induced cycloplegia in children.
  • To assess the impact of pre-treatment with proxymetacaine on children's experience during ophthalmic examinations.

Main Methods:

  • Eighty-eight pediatric patients were assessed in a clinical setting.
  • Parental reports using a grading scale evaluated responses to prior cyclopentolate use.
  • The same grading system assessed patient response to proxymetacaine followed by cyclopentolate.

Main Results:

  • Seventy percent of children experienced distress (crying, unhappiness) with cyclopentolate alone.
  • Ninety-one percent of children showed no adverse reaction and remained comfortable when proxymetacaine preceded cyclopentolate.
  • Pre-treatment with proxymetacaine dramatically improved patient comfort during cycloplegia.

Conclusions:

  • Pre-instillation of proxymetacaine renders cyclopentolate-induced cycloplegia atraumatic in pediatric patients.
  • This method enhances the doctor-patient relationship by reducing fear and improving cooperation.
  • Atraumatic cycloplegia is achievable and beneficial in pediatric ophthalmology.
Abstract

Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...