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Surgery in cystic fibrosis--a 20-year review

A T Westwood1, J D Ireland, M D Bowie

  • 1Cystic Fibrosis Clinic, Red Cross War Memorial Children's Hospital.

South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
|April 16, 1998
PubMed

Insights

Cystic fibrosis (CF) patients frequently require surgery, often for meconium ileus. When indicated, surgical intervention for CF demonstrates low mortality and morbidity rates, making it a viable treatment option.

Area of Science:

  • Pediatric Surgery
  • Pulmonary Medicine
  • Gastroenterology

Background:

  • Cystic Fibrosis (CF) is a genetic disorder affecting multiple organs.
  • Surgical intervention is sometimes necessary for CF complications.
  • Historical data on surgical outcomes in CF patients is valuable.

Purpose of the Study:

  • To analyze the surgical histories of pediatric patients with Cystic Fibrosis (CF).
  • To determine the types and frequency of surgeries performed for CF-related conditions.
  • To evaluate the morbidity and mortality associated with surgery in CF patients.

Main Methods:

  • Retrospective review of surgical histories for 111 pediatric patients diagnosed with Cystic Fibrosis (CF).
  • Data collected between 1972 and 1991.
  • Categorization of surgeries based on relation to CF, including abdominal and thoracic procedures.

Main Results:

  • 154 operations were performed on 57 children.
  • 84 operations were directly related to CF, with meconium ileus being the most common indication (26 major abdominal procedures).
  • Low rates of mortality (1 death within one month) and complications (11.9% anesthetic, 9.2% post-operative) were observed.

Conclusions:

  • Patients with Cystic Fibrosis (CF) have a high likelihood of requiring surgical intervention during their lifetime.
  • When surgery is indicated for CF, it can be performed with acceptable low morbidity and mortality.
  • Surgical management is a critical component in the comprehensive care of pediatric patients with Cystic Fibrosis (CF).

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