Related Experiment Video
Updated: Sep 13, 2026

The Forced Swim Test as a Model of Depressive-like Behavior
Published on: March 2, 2015
[Depression as a psychophysical illness phenomenon]
1Psychiatrische Universitätspoliklinik, Kantonsspital Basel.
Abstract:
The old Greeks understood depression as a somatic process as well as an oppressing experience. Disturbances of the transmitters, ligands and receptors and the decoupling of the feedback-systems of the hypothalamic-pituitary-adrenocortical systems with an impairment of the immune-system are experienced as depression with its narcissistic depletion and orientation towards conscience and order. Thereby the conscious experience is less differentiated than the complex somatic processes which are proving it. Under a holistic aspect it is, however, doubtful whether psychotherapy can be differentiated from somatotherapy. Each psychotherapy acts through the sensory organs on the body like somatotherapy. Until now, however, only a few results of research are known concerning somatic parameters, for example of the transmitter- and immune-processes of the body, during a simple, with preference cognitive-behavioral psychotherapy. For that the researchers would have to be trained to reach a reliable evaluation of its somatic parameters. As it was proved scientifically, the influence onto somatic functions is even possible with complex psychotherapeutic methods such as hypnosis. Such research is until now still relatively seldom done. This may be due, on one hand, to the fact that many psychiatrists and other physicians still maintain the fatal psychophysical dualism and on the other hand, that the pharmaceutical industry has until now not had an interest in comparative investigations concerning the effects of psychotherapy and pharmacotherapy.
Related Concept Videos
Depression: Overview
Introduction to Psychological Disorders
Deviant Behavior
Deviance in behavior refers to actions or thought patterns that significantly diverge from societal norms or...
Theoretical Approaches to Psychological Disorder
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
Depressive Disorders: MDD and Dysthymia
Psychodynamic Therapy
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

