Related Experiment Video
Updated: Aug 11, 2026
10:22
Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum
Published on: December 4, 2015
[Malaria therapy; ups and downs, how much longer?]
1Afd. Inwendige Geneeskunde, onderafd. Infectieziekten, Tropische Geneeskunde en Aids, Universiteit van Amsterdam/Academisch Medisch Centrum.
Nederlands Tijdschrift Voor Geneeskunde
|April 18, 1998
Summary
Natural antimalarials like quinine and artemisinin are effective, but resistance and cost hinder new drug development. International collaboration is crucial for malaria research and public health.
Area of Science:
- Pharmacology
- Tropical Medicine
- Drug Discovery
Context:
- Historical use of natural antimalarials (quinine, artemisinin) spans centuries.
- Synthetic antimalarials emerged due to wartime necessity, but face resistance.
- Current antimalarials are often too expensive for widespread deployment.
Purpose:
- To highlight the challenges in developing new antimalarial drugs.
- To emphasize the need for international cooperation in malaria research.
- To advocate for Dutch researchers' involvement in global malaria control efforts.
Summary:
- Antimalarial drug development faces hurdles including resistance to existing treatments and high costs of newer synthetics.
- The pharmaceutical industry finds new antimalarial development financially prohibitive.
- Emerging collaborative frameworks involving industry, research, government, and international bodies are essential.
Impact:
- Increased global cooperation can accelerate the development of affordable and effective antimalarials.
- Dutch researchers can contribute significantly to malaria control for humanitarian and self-interested reasons.
- Strengthening international malaria research benefits global public health and disease prevention.
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