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Radiological findings in developmental delay

G B Schaefer1, J B Bodensteiner

  • 1Department of Pediatrics, Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha 68198-5430, USA.

Seminars in Pediatric Neurology
|April 21, 1998
PubMed
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Neuroimaging reveals frequent abnormalities in patients with nonsyndromic mental retardation and global developmental delays. This review guides the cost-benefit analysis for neuroimaging in these pediatric neurodevelopmental disorders.

Area of Science:

  • Pediatric Neurology
  • Neuroradiology
  • Developmental Pediatrics

Background:

  • Nonsyndromic mental retardation and global developmental delays are common pediatric conditions.
  • Neuroimaging is a critical tool for identifying underlying etiologies.
  • The utility and cost-effectiveness of neuroimaging require careful consideration.

Purpose of the Study:

  • To review neuroimaging findings in patients with nonsyndromic mental retardation and global developmental delays.
  • To discuss the frequency and types of abnormal neuroimaging findings.
  • To evaluate the cost-benefit of neuroimaging in this population and its extension to milder delays.

Main Methods:

  • Literature review of neuroimaging studies in pediatric populations with developmental delays.

Related Experiment Videos

  • Analysis of reported frequencies and types of neuroimaging abnormalities.
  • Discussion of clinical guidelines and cost-effectiveness.

    • Main Results:

    • Abnormal neuroimaging findings are frequent in patients with nonsyndromic mental retardation and global developmental delays.
    • Specific patterns of abnormalities correlate with different etiologies.
    • Cost-benefit analysis suggests targeted neuroimaging based on clinical presentation.

    Conclusions:

    • Neuroimaging is valuable for diagnosing the cause of developmental delays.
    • Careful patient selection optimizes the diagnostic yield and cost-effectiveness of neuroimaging.
    • Consideration should be given to extending neuroimaging to milder developmental delays and other neurodevelopmental disorders.