Stroke: a double-edged sword for cleaving clots?
Related Experiment Video
Updated: Oct 30, 2026

The Stroke Preclinical Assessment Network Multi-Laboratory Model of Thromboembolic Stroke with Thrombolysis: TE-MCAo
Published on: December 19, 2025
1The CNS Inflammation Group, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.
Abstract:
The discovery that tissue plasminogen activator can promote neuronal degeneration has uncovered a novel pathway leading to neuronal cell death and raises important issues concerning the use of tissue plasminogen activator as a thrombolytic therapy for stroke.
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