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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

[Immunology in clinical practice. VII. Psoriasis]

J D Bos1, M A de Rie

  • 1Afd. Huidziekten, Academisch Medisch Centrum, Amsterdam.

Nederlands Tijdschrift Voor Geneeskunde
|April 29, 1998
PubMed

A new hypothesis of the pathogenesis of psoriasis holds that psoriasis is an epidermal hyperproliferative disorder resulting from abnormal interaction between T cells and basal layer stem cell keratinocytes. New therapies aimed at reducing T cell activity are most successful, as exemplified by the efficacy of systemic cyclosporine in severe cases of psoriasis. New developments in immunogenetics and immunodermatology are anticipated and it is expected that they will fully explain the chain of pathological events.

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