Related Experiment Video
Updated: Aug 10, 2026
07:50
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Clinical aspects of acne
1Department of Dermatology, SUNY Health Science Center at Brooklyn 11203-2012, USA.
Dermatology (Basel, Switzerland)
|April 29, 1998
Summary
Acne vulgaris presents in diverse clinical forms, ranging from mild to severe inflammatory or comedonal types. Patient response to acne treatment varies, influenced by lesion type, distribution, age, and complicating factors.
Area of Science:
- Dermatology
- Clinical Medicine
Background:
- Acne vulgaris exhibits diverse clinical presentations.
- Lesion characteristics (type, number, severity) vary significantly.
- Inflammatory acne has numerous subtypes.
Purpose of the Study:
- To characterize the varied clinical forms of acne vulgaris.
- To explore factors influencing therapeutic response in acne patients.
- To understand how lesion distribution, age, and complicating factors affect acne management.
Main Methods:
- Clinical assessment of acne lesion types and severity.
- Categorization of patients based on therapeutic responsiveness.
- Analysis of influencing factors such as lesion distribution and patient age.
Main Results:
- Acne vulgaris manifests as mild, moderate, or severe forms, predominantly comedonal or inflammatory.
- Therapeutic response is not solely predicted by lesion number or extent.
- Clinical presentation and treatment outcomes are modified by lesion distribution, patient age, and complicating factors.
Conclusions:
- Acne vulgaris requires individualized assessment due to its varied clinical forms.
- Therapeutic strategies for acne must consider patient-specific factors beyond lesion characteristics.
- Understanding the interplay of lesion type, distribution, age, and complicating factors is crucial for effective acne vulgaris management.
Related Concept Videos
01:21Accessory Structures of the Skin: Sebaceous Glands
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
01:23Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
01:30Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
01:27The Skin Microbiota
The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
01:29Staphylococcal Skin Infections
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
01:27Acne Infection
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...