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Updated: Aug 6, 2026
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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Anticancer agents. III. 4,4'-(Hexane-1,6-diyl)bis(piperazine-2,6-dione)
1Department of Chemistry, Peking University, Beijing, People's Republic of China.
Summary
The crystal structure of C14H22N4O4 reveals a molecule with a crystallographic inversion center. Its methylene chain adopts a fully extended conformation in the solid state.
Area of Science:
- Crystallography
- Molecular structure determination
Background:
- Understanding molecular conformation is crucial in solid-state chemistry.
- C14H22N4O4 is a compound of interest for its potential applications.
Purpose of the Study:
- To elucidate the crystal structure of C14H22N4O4.
- To characterize the molecular geometry and packing in the crystalline state.
Main Methods:
- Single-crystal X-ray diffraction was employed.
- Crystallographic data was collected and analyzed.
Main Results:
- The molecule of C14H22N4O4 was found to possess a crystallographic inversion center.
- The methylene chain within the molecule adopts a fully extended conformation.
Conclusions:
- The determined crystal structure provides insights into the solid-state behavior of C14H22N4O4.
- The extended methylene chain conformation may influence the material properties.
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