Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thyroid-pituitary feedback during iodine repletion

M C Gershengorn, J Wolff, P R Larsen

    The Journal of Clinical Endocrinology and Metabolism
    |September 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Response to the comment on "Robotic-controlled laser osteotome versus manually controlled osteotomy for interdental osteotomies: a cadaveric study".

    International journal of oral and maxillofacial surgery·2026
    Same author

    Robotic-controlled laser osteotome versus manually controlled osteotomy for interdental osteotomies: a cadaveric study.

    International journal of oral and maxillofacial surgery·2025
    Same author

    Automated and app-based activation of first responders for prehospital cardiac arrest: an analysis of 16.500 activations of the KATRETTER system in Berlin.

    Scandinavian journal of trauma, resuscitation and emergency medicine·2023
    Same author

    Forecasting admissions in psychiatric hospitals before and during Covid-19: a retrospective study with routine data.

    Scientific reports·2022
    Same author

    Outcomes of gallstone complications during the COVID pandemic.

    The British journal of surgery·2021
    Same author

    [Prioritization of intensive medical treatment places - Concept proposal].

    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2021
    Same journal

    Genetic and Clinical Factors Associated With Metformin Plasma Concentrations Following an Acute Metformin Challenge.

    The Journal of clinical endocrinology and metabolism·2026
    Same journal

    Continuous glucose monitoring-derived time in range is associated with changes in arterial stiffness in type 2 diabetes.

    The Journal of clinical endocrinology and metabolism·2026
    Same journal

    Association of the Primary Aldosteronism Severity Classification with Lateralization and Treatment Outcomes.

    The Journal of clinical endocrinology and metabolism·2026
    Same journal

    From Premature Adrenarche to Adult Metabolic Risk and Hyperandrogenism: A Systematic Review and Meta-Analysis.

    The Journal of clinical endocrinology and metabolism·2026
    Same journal

    Open-Label 9-Year Follow-Up Extension Phase 2 Study of Once-Weekly Somatrogon in Children With Growth Hormone Deficiency.

    The Journal of clinical endocrinology and metabolism·2026
    Same journal

    Correction to: "CAHQL: A Patient-Reported Outcome Instrument to Assess Health-Related Quality of Life in Congenital Adrenal Hyperplasia".

    The Journal of clinical endocrinology and metabolism·2026
    See all related articles

    Iodine repletion in a patient with a congenital iodide-trapping defect normalized triiodothyronine (T3) and thyroxine (T4) levels. Thyrotropin (TSH) regulation shifted from T3 to T4 influence as thyroid hormone levels changed.

    Area of Science:

    • Endocrinology
    • Thyroid Physiology

    Background:

    • Severe iodine deficiency can impair thyroid hormone production.
    • Congenital iodide-trapping defects present unique challenges in managing thyroid hormone levels.

    Observation:

    • This study monitored serum triiodothyronine (T3), thyroxine (T4), and thyrotropin (TSH) in a patient with a congenital iodide-trapping defect during iodine repletion.
    • Thyroid hormone and TSH levels were tracked over 32 days following the initiation of iodine therapy.

    Findings:

    • Serum T3 became detectable within 12 hours and normalized by 36 hours, eventually reaching supra-normal levels.
    • Serum T4 remained undetectable for 9 days before rising to normal levels.
    • Serum TSH initially decreased rapidly, correlating with T3 levels, and later decreased more slowly, correlating with T4 levels.

    Related Experiment Videos

    Implications:

    • The findings suggest that both T3 and T4 may directly regulate thyrotropin secretion.
    • This provides insight into the dynamic feedback mechanisms controlling thyroid hormone homeostasis.
    • Understanding these regulatory shifts is crucial for managing patients with iodine deficiency disorders.