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Neuroprotection by selegiline and other MAO inhibitors
1Department of Clinical Neurology, University College, London Hospitals, United Kingdom.
Abstract:
A proposal for the nomination of the father of monoamine oxidase inhibitors is presented. A brief history of the human clinical pharmacology of selegiline is considered including the results of two major prospective ongoing clinical trials and recent evidence on the effects of sustained selegiline therapy on postural blood pressures in parkinsonians is discussed.