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A prospective cohort study on the survival experience of under five children in rural western India
Insights
Child survival is significantly impacted by birth weight and nutritional status. Key interventions for improving child survival include immunization and breastfeeding practices.
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- Child survival remains a critical global health challenge.
- Understanding determinants of child mortality is essential for effective public health strategies.
Purpose of the Study:
- To investigate the influence of birth weight, nutrition, immunization, and socio-medical factors on child survival up to five years of age.
- To identify key factors affecting child mortality in a rural Indian population.
Main Methods:
- Prospective cohort study involving 4129 children followed from birth to five years.
- Data collection included anthropometric measurements, morbidity, immunization status, and verbal autopsy for cause of death.
- Statistical analysis utilized Kaplan-Meier survival curves and multivariate analysis.
Main Results:
- Neonatal, infant, and under-five mortality rates were 37, 60, and 79 per 1000 live births, respectively.
- Diarrhea and acute respiratory infections (ARI) were major causes of mortality.
- Birth weight, immunization status, and nutritional status (mother and child) were significant predictors of mortality.
Conclusions:
- Birth weight is a crucial determinant of child survival throughout the first five years of life.
- Comprehensive child survival strategies must prioritize immunization and breastfeeding.
Objective:
To study the role of birth weight, nutrition, immunization and other medical as well as social factors in determining child survival.
Design:
A prospective cohort study.
Setting:
45 villages in Shirur Development Block in Pune District in Maharashtra.
Methods:
A cohort of 4129 children were followed from birth till 5 years of age. Weight and length/height of the child was measured at birth and at 3 monthly home visits. Information was also obtained on common childhood morbidities, immunization status and other bio-medical factors. Cause of death was ascertained by verbal autopsy.
Results:
The neonatal, infant and underfive mortality was rates were estimated to be 37, 60 and 79 per 1000 live births, respectively. Diarrhea and ARI contributed to the major mortality burden. The Kaplan Meier Survival curve showed a sharp fall in the neonatal period, a less rapid decline in the post-neonatal period followed by a marginal fall in the post-infancy period till 5 years age. Girls had a better survival in the early neonatal period but the trend reversed in the late neonatal period. Normal birth weight children had better survival curves compared to low birth weight children. Survival improved with increasing birth order. Multivariate analysis revealed that birth weight, immunization status, and mother's and child's nutritional status influenced infant and under five mortality.
Conclusion:
Birth weight continues to exert its influence not only on survival/mortality in early life but even as late as 5 years of age. Strategies to improve child survival should include immunization and breastfeeding.
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