Related Experiment Videos
Bioelectrical impedance spectroscopy (BIS) in young children with acute and semi-acute hydration disorders:
M Mazariegos1, C Pithan, A Meyer
1Center for Studies of Sensory Impairment, Aging and Metabolism (CeSSIAM), Guatemala City, Guatemala.
Insights
Bioelectrical impedance spectroscopy (BIS) is feasible and reliable for assessing hydration in children. Extracellular resistance measurements showed high reproducibility, indicating its potential use in pediatric critical care.
Area of Science:
- Pediatric critical care medicine
- Biomedical engineering
- Clinical physiology
Background:
- Accurate hydration assessment is crucial in pediatric critical care.
- Bioelectrical impedance spectroscopy (BIS) offers a non-invasive method for fluid status evaluation.
- Limited data exists on BIS feasibility and reliability in young children with acute hydration disorders.
Purpose of the Study:
- To evaluate the feasibility and reliability of BIS for assessing hydration in young children.
- To determine the reproducibility of whole-body and segmental BIS measurements in this population.
- To explore the potential application of BIS in critically ill pediatric patients.
Main Methods:
- Feasibility and reliability of BIS were assessed in 42 children (4-147 months) with acute hydration disorders.
- Whole-body and segmental measurements were performed using a BIS analyzer (Xitron 4000B).
- Extracellular (RECW) and intracellular (RICW) resistance were calculated using manufacturer software; reproducibility was analyzed using correlation coefficients (r) and technical error of measurement (TEM).
Main Results:
- BIS measurements were feasible in young children, with several hundred measurements successfully obtained.
- Extracellular resistance (RECW) demonstrated high reproducibility (r = 0.99) with low TEM (1-3.5%) across all segments.
- Reliability for intracellular resistance (RICW) was lower than for RECW.
Conclusions:
- BIS is a feasible and highly reproducible technique for assessing extracellular fluid status in young children, even those with acute hydration disorders.
- The high reproducibility of RECW suggests BIS can be reliably applied in pediatric critical care settings.
- Further research may explore the application of BIS for intracellular fluid assessment in this population.
Abstract:
This study aimed to evaluate the feasibility and reliability of bioelectrical impedance spectroscopy in young children suffering of acute hydrational disorders. Whole body and segmental measurements were carried out in a group of 42 of children aged 4 to 147 months, using a BIS analyzer (Xitron 4000B). This phase of the study involved several hundred of BIS measurement, which showed the feasibility of using this technique in young children. Using the sweep mode and the modeling software provided for the manufacturer of the instrument, the resistance of the extracellular (RECW) and intracellular (RICW) compartment was calculated. Correlation coefficient (r) and technical error of measurement (TEM) were obtained from paired BIS measurements. RECW showed to be highly reproducible (r = 0.99), with a relatively low TEM (from 1 to 3.5%), across all segments. The reliability was markedly lower respect to RICW, which shows the potential application of BIS technique even in critically ill young child populations.