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Clozapine-induced agranulocytosis: a case report. Immunopathophysiological considerations
A A van de Loosdrecht1, H J Faber, P Hordijk
1Department of Internal Medicine, State University Hospital Groningen, Netherlands. a.a.vandeLoosdrecht@int.azg.nl
The Netherlands Journal of Medicine
|May 9, 1998
Abstract:
A 46-year-old woman is described with a clozapine-induced agranulocytosis. She was treated with a broad-spectrum antibiotic and supportive care was provided with granulocyte colony-stimulating factor (G-CSF). Immune-mediated mechanisms of clozapine-induced agranulocytosis and the role of haematopoietic growth factors are discussed.