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Related Experiment Videos

Continuous non-contact corneal pachymetry with a high speed reflectometer

M Böhnke1, P Chavanne, R Gianotti

  • 1Department of Ophthalmology, University of Bern, Switzerland.

Journal of Refractive Surgery (Thorofare, N.J. : 1995)
|May 9, 1998
PubMed
Summary

This study presents a new optical pachymeter for precise, non-contact corneal thickness monitoring. The instrument accurately measures changes in corneal thickness over time, even after laser procedures.

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Optical Metrology

Background:

  • Corneal thickness monitoring is crucial for diagnosing and managing various eye conditions.
  • Existing methods may lack precision, speed, or non-contact capabilities.
  • Assessing corneal changes under ambient conditions is challenging due to surface reflectivity and moisture loss.

Purpose of the Study:

  • To develop and validate a novel instrument for high-speed, high-precision, non-contact corneal thickness measurement.
  • To evaluate the stability and reproducibility of measurements over extended periods.
  • To assess performance under conditions of low surface reflectivity and unmoistened corneas.

Main Methods:

  • An optical pachymeter, based on a broad-band, all-fiber Michelson interferometer, was employed.

Related Experiment Videos

  • Central corneal thickness of enucleated porcine eyes was continuously monitored.
  • Measurements were conducted on corneas with intact, abraded, or laser-keratectomized epithelia for up to 1 hour.

    • Main Results:

    • The instrument achieved a precision of 1 micrometer for monitoring unmoistened corneal thickness.
    • Deturgescence (corneal thinning) rates ranged from 1 to 5 micrometers/minute.
    • Corneas with intact epithelium showed the least thinning (10%), while laser-keratectomized corneas showed the most (28.5%) over 1 hour.

    Conclusions:

    • The interferometric method enables precise (1 micrometer) continuous, non-contact corneal thickness measurement for up to 1 hour.
    • The device functions effectively even with altered corneal surface conditions post-photoablative keratectomy.
    • This technology holds potential for real-time monitoring of ablation depths during ophthalmic surgical procedures.