Related Experiment Video
Updated: Aug 10, 2026
05:53
Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
Published on: July 6, 2013
[Parvovirus B19 as infectious agent in infants]
M P Angulo Barreras1, A Fernández López, M Pérez de Saracho Taramona
1Departamento de Pediatría, Hospital de Cruces, Baracaldo.
Anales Espanoles De Pediatria
|May 9, 1998
Summary
Human parvovirus B19 infection in infants can cause diverse clinical symptoms, including arthritis and hematologic issues. Further research is needed to fully understand the significance of B19 parvovirus in pediatric diseases.
Area of Science:
- Virology
- Pediatrics
- Infectious Diseases
Context:
- Human parvovirus B19 is a known pathogen causing aplastic crises and erythema infectiosum.
- Its association with a broad range of clinical manifestations in infants is not fully understood.
Purpose:
- To investigate the clinical spectrum of parvovirus B19 infection in serologically confirmed infants.
- To better comprehend the diverse clinical presentations associated with B19 parvovirus in a pediatric population.
Summary:
- A review of 15 infants with positive IgM antibodies for parvovirus B19 revealed varied clinical presentations.
- Common findings included arthritis (5 cases) and hematologic disturbances (5 cases), alongside febrile syndrome, liver dysfunction, and neuromyelitis.
- The study observed a higher incidence during winter months, with no significant sex predilection.
Impact:
- This study highlights the wide-ranging clinical impact of parvovirus B19 in infants, extending beyond its typical presentations.
- It underscores the need for increased awareness and further research into the pathogenesis and long-term significance of B19 parvovirus infections in children.
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