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[Bilateral endogenous endophthalmitis]

R Augsten1, E Königsdörffer, A Oehme

  • 1Klinik für Augenheilkunde der Friedrich-Schiller-Universität Jena.

Klinische Monatsblatter Fur Augenheilkunde
|May 13, 1998
PubMed
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This case report details a rare instance of endogenous endophthalmitis in both eyes, initially suspected bacterial and later confirmed fungal (Aspergillus). Despite treatment, the patient succumbed to systemic Aspergillus infection, highlighting the poor prognosis of this condition.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Transplantation Medicine

Background:

  • Endogenous endophthalmitis is a severe intraocular infection, often a complication of systemic infections.
  • Aspergillus-induced endophthalmitis is rare, typically associated with immunosuppression or severe illness.
  • This case involves a kidney transplant recipient on immunosuppressive therapy.

Observation:

  • A 51-year-old man presented with sequential endogenous endophthalmitis in both eyes.
  • The right eye infection was initially presumed bacterial.
  • The left eye infection, occurring eight weeks later, was diagnosed as Aspergillus endophthalmitis.

Findings:

  • The patient underwent bilateral pars-plana-vitrectomy and received antibacterial and antimycotic treatments.

Related Experiment Videos

  • Bacterial endophthalmitis in the right eye resolved; the left eye stabilized post-operatively.
  • The patient ultimately died from septic shock due to systemic Aspergillus infection.

    • Implications:

    • This case represents a unique presentation of bilateral endogenous endophthalmitis caused by distinct pathogens (bacteria and Aspergillus).
    • It underscores the critical, albeit poor, prognosis of endogenous endophthalmitis, especially in immunocompromised patients.
    • Early diagnosis and aggressive multimodal treatment are crucial for managing endogenous endophthalmitis.