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Updated: Aug 11, 2026
07:45
Retroductal Nanoparticle Injection to the Murine Submandibular Gland
Published on: May 3, 2018
Neonatal suppurative submandibular sialadenitis: a rare clinical entity
K Ungkanont1, T Kolatat, W Tantinikorn
1Department of Otolaryngology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Summary
Neonatal submandibular sialadenitis, an extremely rare condition, was observed in a premature infant. Prompt treatment with antibiotics led to successful resolution of the Pseudomonas aeruginosa infection.
Area of Science:
- Pediatric Infectious Diseases
- Neonatology
- Otolaryngology
Background:
- Submandibular sialadenitis is exceptionally rare in neonates, with only four prior reported cases of isolated submandibular gland infection.
- This case contributes to the limited understanding of this condition in the neonatal population.
Observation:
- A premature newborn presented with fever and right submandibular swelling at 8 days old.
- Pus was observed extruding from Wharton's duct, and culture identified Pseudomonas aeruginosa.
Findings:
- The infant received conservative management including hydration and intravenous ceftazidime for 14 days.
- Computed tomography (CT) scan excluded calculi and anatomical abnormalities.
- The infection resolved completely with no recurrence at two months follow-up.
Implications:
- Prematurity and dehydration are potential predisposing factors for neonatal submandibular sialadenitis.
- This case highlights the importance of considering rare infections in neonates presenting with swelling and fever.
- Successful conservative management underscores the efficacy of prompt antibiotic therapy.
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