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[Preconceptional control in diabetic women]
M T García Ingelmo1, L Herranz de la Morena, P Martín Vaquero
1Servicio de Endocrinología, Hospital Universitario La Paz, Madrid.
Revista Clinica Espanola
|May 15, 1998
Summary
Preconceptional control (PCC) for insulin-dependent diabetic patients improved glycemic control before pregnancy. While PCC did not reduce fetal morbidity, further research is needed to understand congenital malformation causes.
Area of Science:
- Reproductive Medicine
- Endocrinology
- Obstetrics
Background:
- Preconceptional control (PCC) is crucial for managing diabetes in pregnancy.
- Evaluating the impact of PCC on pregnancy outcomes in insulin-dependent diabetic patients.
Observation:
- A Preconceptional Clinic managed 28 insulin-dependent diabetic patients from 1992-1996.
- 19 patients achieved pregnancy, with 12 completing full pregnancies.
Findings:
- Patients undergoing PCC showed lower HbA1c levels compared to controls.
- No significant difference in fetal morbidity was observed between groups.
- A severe congenital malformation occurred in the PCC group despite normal periconceptional HbA1c.
Implications:
- PCC positively impacts glycemic control in diabetic pregnancies.
- Additional teratogenic factors beyond HbA1c require investigation.
- Further research is essential to elucidate causes of congenital malformations in diabetic pregnancies.