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Emerging targets for the development of novel antifungal therapeutics
A H Groll1, A J De Lucca, T J Walsh
1Immunocompromised Host Section, National Cancer Institute, NIH, Bethesda, MD, USA.
Trends in Microbiology
|May 16, 1998
Abstract:
Invasive mycoses have become important causes of morbidity and mortality in immunocompromised patients. New approaches for antifungal therapy are required to meet the challenges imposed by these life-threatening infections. Such approaches are being developed through identification of novel biochemical and molecular targets of pathogenic fungi.