[Methodological approaches of I.V. Davydovskiĭ from the standpoint of the pathophysiologist]

I.V. Davydovsky's principles of etiology, pathogenesis and disease are, in fact, biological concept of the theory of pathology. The main point of this concept is consideration of general pathological processes (regeneration, inflammation, thrombosis, immunity, fever, etc.) as adaptive natural-historical events the importance of which for an individual may vary in a wide range. A prospective direction in further development of I.V. Davydovsky's concept is the study of the role of regulation system at various levels in the storage of genetic information and its realization. This determines the degree of usefulness of these adaptive processes.