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Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
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Model for action of local anaesthetics

A G Lee

    Nature
    |August 12, 1976
    PubMed
    Summary

    Local anesthetics alter nerve membrane lipids, causing sodium channels to close and induce anesthesia. This model explains the mechanism of local anesthetic action on nerve signal transmission.

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