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Identification of lymphocyte subsets in pregnancy gingivitis
O M Aboul-Dahab1, M M el-Sherbiny, R Abdel-Rahman
1Faculty of Oral and Dental Medicine, Cairo University.
Egyptian Dental Journal
|January 1, 1994
Summary
Pregnancy gingival health is affected by immune cell changes. Key immune cells like T and B lymphocytes decrease in pregnant women
Area of Science:
- Immunology
- Periodontology
- Obstetrics
Background:
- Pregnancy involves significant physiological changes, potentially impacting immune responses.
- Gingival health can be altered during pregnancy, a condition sometimes referred to as "pregnancy gingivitis".
Purpose of the Study:
- To investigate changes in gingival tissue and peripheral immune cell populations during pregnancy.
- To correlate clinical gingival status with immune cell percentages in pregnant women.
Main Methods:
- Assessed gingival tissue and peripheral blood samples from ten pregnant women across three trimesters.
- Measured percentages of T lymphocytes (T3, T4 subsets) and B lymphocytes.
- Utilized the gingival index (GI) for clinical assessment.
Main Results:
- Gingival index (GI) scores were higher in pregnant women compared to controls.
- A decrease in the percentage of T3, T4, and B lymphocytes was observed in peripheral blood during pregnancy.
- Reduced percentages of these lymphocytes were also noted in gingival tissues of pregnant women.
Conclusions:
- Pregnancy is associated with increased gingival inflammation.
- Immune cell profiles, specifically T and B lymphocyte percentages, are altered in peripheral blood and gingival tissues during pregnancy.