[Treatment of central retinal artery occlusion with thrombolysis via superselective ophthalmic artery...

To investigate the therapeutic effect of thrombolysis via superselective ophthalmic artery catheterization for treatment of central retinal artery occlusion (CRAO).

Urokinase was directly infused via ophthalmic artery (OA) or common carotid artery by catheterization after angiography into 4 eyes of 4 patients with CRAO, The times of onset ranging from 7 to 14 days.

The visual acuity was significantly improved in 2 eyes. No visual change was found in 2 eyes in which the beginning part of internal carotid artery (ICA) or OA was occluded. There was no complications.

Good results were obtained in the eyes in which thrombolysis was launched early in the course of the disease and urokinase was successfully infused into the OA. It seems that there is no effect for the eyes complicated with occlusion in ICA and OA.