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A triazine dye, cibacron blue F3GA, decreases oxacillin resistance levels in methicillin-resistant Staphylococcus
C Shirai1, M Sugai, H Komatsuzawa
1Department of Internal Medicine II, Hiroshima University School of Medicine, Japan.
Antimicrobial Agents and Chemotherapy
|May 21, 1998
Abstract:
Cibacron blue F3GA (CB) was found to reduce the MIC of oxacillin for methicillin-resistant Staphylococcus aureus (MRSA). This effect was not observed with methicillin-susceptible S. aureus. CB alters the resistance level of MRSA through a factor(s) other than mecA-related products, major autolysins, or femAB products. The exact target(s) of CB in causing the effect is unknown.