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Carbohydrate-based combinatorial libraries
1Transcell Technologies Inc., Cranbury, NJ 08512, USA.
Molecular Diversity
|January 1, 1997
Abstract:
Carbohydrate-based combinatorial libraries are tremendously valuable for studying the role of sugars in biology and for expanding accessible molecular diversity needed in broad-based drug screening programs. This review discusses the issues that are relevant to the successful implementation of comprehensive carbohydrate-based combinatorial library programs. In addition, details of oligosaccharide and glycoconjugate libraries constructed using both solid phase and solution phase strategies are presented.