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Updated: Sep 11, 2026

Labeling of Breast Cancer Patient-derived Xenografts with Traceable Reporters for Tumor Growth and Metastasis Studies
Published on: November 30, 2016
[Radiosurgical labeling of non-palpable mammary lesions]
B Aguirre1, L Gutiérrez, D Ortega
1Unidad de Mamografía, Hospital Clínico, Universidad de Chile, Santiago de Chile.
Background:
The frequency of breast cancer is increasing worldwide and mammography allows the diagnosis of concealed lesions.
Aim:
To assess the diagnostic yield for carcinoma of non palpable lesions detected by mammography.
Patients And Methods:
We studied 46 patients, aged 24 to 67 years old, in whom a radiosurgical labeling of non palpable mammary lesions was performed. In all patients, a surgical biopsy was obtained, but the pathological study was available in only 40 patients.
Results:
The mammographic appearance of lesions were microcalcifications in 40% of women, stellate images in 27.5%, asymmetry in density in 5% and the association of microcalcifications and other signs in 20%. Seventy seven percent of lesions were benign. Four patients had an in situ ductal carcinoma, two had a predominantly in situ carcinoma and 4 had an invasive ductal carcinoma.
Conclusions:
Our results are similar to those reported abroad. The finding of 5 minimal carcinomas underscores the effectiveness of mammography as a screening method for breast cancer.

