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B-cell receptor regulation of peripheral B cells
1Department of Immunology, University of Birmingham Medical School, UK. macleicm@novell2.bham.ac.uk
Current Opinion in Immunology
|May 29, 1998
Abstract:
Recent studies indicate that immature B cells compete with recirculating B cells for survival signals. The signals, delivered through the B-cell receptor for antigen, induce immature cells to differentiate into recirculating cells and maintain the survival of recirculating cells. They do not induce proliferation or differentiation to antibody-producing cells.