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Pyoderma gangrenosum of the penis
A M Farrell1, M M Black, A Bracka
1Chelsea and Westminster Hospital, London, U.K.
The British Journal of Dermatology
|May 29, 1998
Summary
Pyoderma gangrenosum of the penis is challenging to treat. Thalidomide or minocycline may be effective when high-dose prednisolone fails.
Area of Science:
- Dermatology
- Urology
Background:
- Pyoderma gangrenosum (PG) is a rare, ulcerative neutrophilic dermatosis.
- Penile involvement in PG is uncommon and presents unique management challenges.
Observation:
- Two male patients presented with penile pyoderma gangrenosum.
- Initial treatment with high-dose prednisolone was insufficient in both cases.
Findings:
- One patient achieved remission with the addition of thalidomide to prednisolone.
- The second patient experienced a cure with minocycline monotherapy.
Implications:
- This case series highlights therapeutic options for refractory penile pyoderma gangrenosum.
- Thalidomide and minocycline represent potential salvage therapies for this rare condition.