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Dealing with drug-induced thrombocytopenia

J G Kelton1

  • 1Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ont.

Unpredictable and potentially life-threatening, immune thrombocytopenia can occur with any drug, at times even after long, uneventful use. Heparin is the most common cause; although the fall in platelet count tends to be modest, these cases are particularly dangerous because of associated thrombosis. Much has been learned about heparin-induced disease, but complex issues remain.

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