Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Genetic renal disease

P Saborio1, J Scheinman

  • 1Department of Pediatrics, Virginia Commonwealth University's Medical College of Virginia, Richmond 23298, USA.

Current Opinion in Pediatrics
|June 3, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Alpha-tocopherol modulates lipoprotein cytotoxicity in obstructive nephropathy.

Pediatric nephrology (Berlin, Germany)·2000
Same author

Diabetes insipidus.

Pediatrics in review·2000
Same author

Transplantation for primary hyperoxaluria in the United States.

Kidney international·1999
Same author

Vitamin E suppresses oxidative stress and glomerulosclerosis in rat remnant kidney.

Pediatric nephrology (Berlin, Germany)·1999
Same author

Increased heat shock protein-70 in unilateral ureteral obstruction in rats.

Molecular genetics and metabolism·1999
Same author

Sickle cell nephropathy.

Journal of the American Society of Nephrology : JASN·1999
Same journal

For health, for beauty, or both? navigating trends as adolescent clinicians.

Current opinion in pediatrics·2026
Same journal

Childhood sleep disorders: practical management for the pediatrician.

Current opinion in pediatrics·2026
Same journal

Advanced therapies in management of pediatric inflammatory bowel disease.

Current opinion in pediatrics·2026
Same journal

Artificial intelligence in pediatric endoscopy for hereditary polyposis syndromes: promises and challenges.

Current opinion in pediatrics·2026
Same journal

Hormonal acne therapies in pediatrics.

Current opinion in pediatrics·2026
Same journal

Clinical implementation of artificial intelligence in adolescent mental healthcare.

Current opinion in pediatrics·2026
See all related articles

Genetic renal diseases have defined pathways impacting kidney health. Understanding these hereditary conditions is crucial for pediatricians to improve patient prognostication and care.

Area of Science:

  • Nephrology
  • Genetics
  • Pediatrics

Background:

  • Genetic renal diseases are increasingly understood with specific genetic definitions.
  • These conditions encompass glomerular, tubular, interstitial, metabolic, and vascular defects.
  • Examples include Alport's syndrome, polycystic kidney disease, and Marfan syndrome.

Purpose of the Study:

  • To highlight the importance of recognizing hereditary pathways to renal disease.
  • To emphasize the role of genetic definitions in prognostication.
  • To underscore the necessity of this knowledge for primary care pediatrics.

Main Methods:

  • Review of genetic renal disease classifications.
  • Categorization of defects by renal structure affected (glomerular, tubular, interstitial, vascular).

Related Experiment Videos

  • Identification of specific hereditary syndromes linked to renal pathology.

    • Main Results:

    • Specific genetic definitions enable accurate prognostication for many renal diseases.
    • Glomerular defects include Alport's syndrome and benign familial hematurias.
    • Tubular/interstitial defects include familial juvenile nephronophthisis and polycystic diseases.
    • Metabolic errors cause glomerular sclerosis and interstitial damage.
    • Vascular defects in syndromes like Marfan's can lead to renal vascular destruction.

    Conclusions:

    • Awareness of hereditary disease pathways to renal disease is essential for pediatricians.
    • Genetic insights facilitate improved prognostication and management strategies.
    • Early recognition of these conditions is key to effective pediatric primary care.