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Clinical experience with pendimethalin (STOMP) poisoning in Taiwan
C C Chuang1, S T Wang, C C Yang
1Department of Emergency Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
Veterinary and Human Toxicology
|June 4, 1998
Summary
Pendimethalin (STOMP) herbicide poisoning is rare but can cause symptoms like nausea and vomiting. Prompt ventilation support is crucial for treating STOMP poisoning cases effectively.
Area of Science:
- Toxicology
- Environmental Health
Background:
- Pendimethalin (STOMP) herbicide shares structural similarities with known methemoglobinemia-inducing nitro compounds.
- Human poisoning reports for STOMP are infrequent, necessitating further clinical investigation.
Purpose of the Study:
- To review and summarize the clinical manifestations of human pendimethalin (STOMP) poisoning.
- To identify key therapeutic interventions for STOMP poisoning.
Main Methods:
- Retrospective case review of 71 pendimethalin (STOMP) poisoning incidents.
- Data collected from the Poison Control Center--Taiwan between September 1986 and September 1997.
- Analysis of clinical symptoms, ingestion routes, and patient outcomes.
Main Results:
- Most cases involved oral ingestion (intentional or accidental), with an average intake of 106.1 ml.
- 20 cases were asymptomatic, 38 showed mild symptoms (nausea, vomiting), and 7 experienced severe effects (retching, hematemesis, seizures).
- Four fatalities occurred, primarily due to co-ingestion with other herbicides and inadequate airway management.
Conclusions:
- Pendimethalin (STOMP) poisoning can present with a range of clinical effects, from asymptomatic to severe.
- Adequate ventilation support is a critical component in managing STOMP poisoning.
- Concurrent ingestion of other pesticides and compromised airway management are associated with poor outcomes.