Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Opiates and infection

J M Risdahl1, K V Khanna, P K Peterson

  • 1University of Minnesota, Department of Clinical and Population Sciences, Veterinary Teaching Hospital, St. Paul 55108, USA.

Journal of Neuroimmunology
|June 4, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of cross-fostering on transfer of maternal immunity to Mycoplasma hyopneumoniae to piglets.

The Veterinary record·2011
Same author

Effect of dietary supplementation of oregano essential oils to sows on colostrum and milk composition, growth pattern and immune status of suckling pigs.

Journal of animal science·2011
Same author

WIN55,212-2 inhibits production of CX3CL1 by human astrocytes: involvement of p38 MAP kinase.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology·2009
Same author

CCL5 evokes calcium signals in microglia through a kinase-, phosphoinositide-, and nucleotide-dependent mechanism.

Journal of neuroscience research·2006
Same author

Transcriptional response of human microglial cells to interferon-gamma.

Genes and immunity·2005
Same author

Leptin increases T-cell immune response in birds.

General and comparative endocrinology·2004
Same journal

Spinal cord microglia exhibit a dysfunctional response to myelin damage.

Journal of neuroimmunology·2026
Same journal

Methodological concerns in the cutoff determination of a flow cytometric MOG-IgG assay: The need for independent validation.

Journal of neuroimmunology·2026
Same journal

Clinical features, imaging findings, and treatment outcomes of optic neuritis associated with anti-CRMP5 antibodies: a systematic review.

Journal of neuroimmunology·2026
Same journal

Serum IDO1 and β-catenin levels in patients with multiple sclerosis with and without atherosclerosis: A case-control study.

Journal of neuroimmunology·2026
Same journal

Neurological sequelae of Long COVID: Pathophysiological mechanisms, diagnostic advances, and therapeutic perspectives.

Journal of neuroimmunology·2026
Same journal

Corrigendum to 'Role of CD40 in prion disease and the immune response to recombinant PrP' [Journal of Neuroimmunology 257 (2013) 21-27/475655].

Journal of neuroimmunology·2026
See all related articles

Opiate use significantly worsens infectious diseases, increasing infection severity and mortality in users. Research explores how opiates affect susceptibility and progression of infections, using animal models to understand these complex interactions.

Area of Science:

  • Infectious Diseases
  • Pharmacology
  • Immunology

Background:

  • Opiate use is associated with a wide range of infectious diseases.
  • Injection drug users experience increased prevalence and severity of bacterial and viral infections.
  • Opiate administration impacts susceptibility and disease progression.

Purpose of the Study:

  • To review the spectrum of infections in opiate users.
  • To understand the effects of opiates on infectious disease susceptibility and progression.
  • To analyze animal models of opiate dependence and infection.

Main Methods:

  • Literature review of infectious diseases in opiate users.
  • Analysis of experimental opiate administration studies.
  • Review of animal models examining opiate-mediated effects on infection.

Related Experiment Videos

Main Results:

  • Opiate use leads to increased morbidity and mortality from infections affecting lungs, GI tract, skin, skeletal system, and CNS.
  • Experimental data enhances understanding of opiate effects on infection.
  • Animal models reveal both harmful and beneficial opiate-mediated effects on infection.

Conclusions:

  • Opiate use poses significant risks for infectious disease complications.
  • Understanding opiate-host-pathogen interactions is crucial for patient outcomes.
  • Further research, including animal models, is needed to elucidate complex effects.