Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Styryl-pyrones from Goniothalamus arvensis

A Bermejo1, M A Blázquez, K S Rao

  • 1Departamento de Farmacología, Farmacognosia y Farmacodinamia, Facultad de Farmacia, Universidad de Valencia, Spain.

Phytochemistry
|June 5, 1998
PubMed
Summary

Researchers isolated two new styryl-pyrones, (+)-garvensintriol and (+)-etharvendiol, and a known cytotoxic compound from Goniothalamus arvensis stem bark. The study established their relative configurations and discussed their absolute stereochemistry.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PSOGI consensus on minimally invasive surgery for peritoneal surface malignancy.

The British journal of surgery·2026
Same author

Presence of sperm-bound antisperm antibodies and their association with semen quality in dogs.

Theriogenology·2026
Same author

Infertility in an American Quarter Horse mare with cervical duplication.

Journal of equine veterinary science·2026
Same author

An Updated Review of <i>Enterococcus cecorum</i> Infections in Poultry.

Avian diseases·2025
Same author

Phylogeny, morphology, and behavior of the new ciliate species <i>Stentor stipatus</i>.

bioRxiv : the preprint server for biology·2024
Same author

Development of video tutorials to help parents manage children with acute illnesses using a modified Delphi method.

Acta paediatrica (Oslo, Norway : 1992)·2023

Area of Science:

  • Natural Product Chemistry
  • Organic Chemistry
  • Pharmacognosy

Background:

  • Goniothalamus arvensis is a plant species known for its potential medicinal properties.
  • The isolation and characterization of novel compounds from plant sources are crucial for drug discovery.

Purpose of the Study:

  • To isolate and elucidate the structures of novel compounds from the stem bark of Goniothalamus arvensis.
  • To determine the relative and absolute stereochemistry of the isolated compounds.
  • To investigate the cytotoxic potential of the isolated compounds.

Main Methods:

  • Extraction of plant material (stem bark of Goniothalamus arvensis).
  • Chromatographic techniques for isolation of compounds (e.g., column chromatography, HPLC).
  • Spectroscopic methods for structure elucidation (e.g., NMR, Mass Spectrometry).

Related Experiment Videos

  • Stereochemical analysis to determine relative and absolute configurations.

    • Main Results:

    • Isolation of two novel styryl-pyrones: (+)-garvensintriol and (+)-etharvendiol.
    • Isolation of a known cytotoxic furano-furone, (+)-goniofufurone.
    • Establishment of the cis-erythro-erythro relative configuration for (+)-garvensintriol.
    • Establishment of the cis-threo-erythro relative configuration for (+)-etharvendiol.
    • Discussion of the absolute stereochemistry of the isolated compounds.

    Conclusions:

    • The stem bark of Goniothalamus arvensis contains novel styryl-pyrones with defined stereochemistry.
    • The isolated compounds, including (+)-goniofufurone, may possess cytotoxic properties warranting further investigation.
    • This study contributes to the understanding of the chemical diversity within the Goniothalamus genus.