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[Latent thyroid diseases in obesity]

F Festuccia1, A Romiti, R Buzzetti

  • 1Cattedra di Endocrinologia, Università La Sapienza, Roma.

Recenti Progressi in Medicina
|June 5, 1998
PubMed
Summary

Obese individuals frequently have undiagnosed thyroid disease, including goiter and chronic thyroiditis. Overweight patients also show a higher incidence of carcinoma in single thyroid nodules.

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Area of Science:

  • Endocrinology
  • Obesity Medicine
  • Thyroidology

Background:

  • Obesity is a growing global health concern.
  • Thyroid disorders are common and can be influenced by various factors.
  • The relationship between obesity and thyroid disease requires further investigation.

Purpose of the Study:

  • To investigate the prevalence of undiagnosed thyroid diseases in obese subjects.
  • To analyze the correlation between obesity, age, sex, and thyroid disease.
  • To compare thyroid nodule characteristics in obese versus normal-weight individuals.

Main Methods:

  • Cross-sectional study of 2672 obese subjects (2324 females, 348 males).
  • Stratification by age, sex, and body mass index (BMI).
  • Comparison of thyroid disease prevalence between obese and normal-weight populations.

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Main Results:

  • 22% of obese subjects without iodine deficiency had undiagnosed thyroid disease (18%).
  • Goiter was more frequent in obese adult males.
  • Chronic thyroiditis predominantly affected females (9:1 ratio).
  • Carcinoma in single thyroid nodules was higher in overweight (5-6%) versus normal-weight individuals.

Conclusions:

  • Obesity is associated with a significant prevalence of undiagnosed thyroid conditions.
  • Specific thyroid conditions like goiter and chronic thyroiditis show distinct patterns in obese populations.
  • Overweight individuals may have an increased risk of thyroid carcinoma within single nodules.