Jove
Visualize
Contact Us

Related Experiment Videos

Valvular endocarditis due to Mycobacterium tuberculosis

K Klingler1, O Brändli, M Doerfler

  • 1Division of Pulmonary and Critical Care Medicine, NYU Medical Center and Bellevue Chest Service, New York 10016, USA.

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
|June 5, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A participatory photovoice investigation of community assets, barriers, and opportunities to curb the opioid epidemic.

Journal of substance use and addiction treatment·2025
Same author

Risks for tuberculosis in Kazakhstan: implications for prevention.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2017
Same author

The new epidemic of non-communicable disease in people living with the human immunodeficiency virus.

Public health action·2015
Same author

Tuberculosis report among injection drug users and their partners in Kazakhstan.

Public health·2015
Same author

Elevated IP-10 and IL-6 from bronchoalveolar lavage cells are biomarkers of non-cavitary tuberculosis.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2013
Same author

Closure of the abdominal wall with acellular dermal allograft in intestinal transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2012
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Tuberculous valvular endocarditis is rare, usually seen in immunocompromised individuals. This report details the first isolated case in an immunocompetent patient with severe mitral regurgitation caused by Mycobacterium tuberculosis.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Pathology

Background:

  • Tuberculous granulomas in heart valves are uncommon.
  • Typically associated with disseminated tuberculosis in immunocompromised patients.

Observation:

  • A case of isolated tuberculous valvular endocarditis in an immunocompetent patient.
  • Severe mitral valve regurgitation due to anterior leaflet perforation.
  • Mycobacterium tuberculosis cultured from mitral valve vegetations.

Findings:

  • First reported case of isolated tuberculous valvular endocarditis.
  • Demonstrates M. tuberculosis can cause isolated valvular disease in immunocompetent hosts.

Implications:

  • Highlights the diverse clinical presentations of tuberculosis.

Related Experiment Videos

  • Suggests considering tuberculosis in valvular heart disease, even in immunocompetent individuals.
  • Expands understanding of Mycobacterium tuberculosis pathogenicity.