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Cell receptors for picornaviruses as determinants of cell tropism and pathogenesis
1School of Animal and Microbial Sciences, Divn of Microbiology, University of Reading, UK. d.j.evans@reading.ac.uk
Trends in Microbiology
|June 6, 1998
Abstract:
Recent studies have identified at least nine distinct receptors used by the piconaviruses for cell entry. Does the evolution of receptor usage correlate with the different tropisms observed in this group of viruses, and does this influence pathogenesis, or is it the consequence of another selection mechanism that favours virus survival?