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[Prostatectomy for prostate cancers]

H Ishida1, T Hachiya, Y Yamanaka

  • 1Dept. of Urology, Nihon University School of Medicine, Tokyo, Japan.

Gan to Kagaku Ryoho. Cancer & Chemotherapy
|June 9, 1998
PubMed
Summary
This summary is machine-generated.

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Radical prostatectomy offers excellent survival for localized prostate cancer. However, some early-stage prostate cancers may be curable without surgery, challenging traditional treatment approaches.

Area of Science:

  • Urology
  • Oncology
  • Surgical Oncology

Context:

  • Radical prostatectomy is a primary treatment for curable prostate cancer.
  • Long-term survival is excellent for organ-confined disease.
  • Minimal extra-organ invasion may still allow for cure with surgery.

Purpose:

  • To evaluate the efficacy of radical prostatectomy for prostate cancer.
  • To explore alternative curative strategies for specific prostate cancer cases.
  • To identify prostate cancers that may not require surgical intervention.

Summary:

  • Radical prostatectomy can cure completely extirpable prostate cancer, with excellent long-term survival for organ-confined disease.
  • Cure is also possible in selected cases with minimal extra-organ invasion, potentially enhanced by preoperative hormonal therapy.

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  • However, some extirpable prostate cancers may be cured without surgery, supported by epidemiological data and conservative treatment observations.
  • Impact:

    • Highlights the need to differentiate between surgically curable and non-lethal prostate cancers.
    • Suggests a re-evaluation of treatment paradigms for early-stage prostate cancer.
    • Emphasizes identifying prostate cancers that will not impact patient mortality during their natural lifespan.