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Parotid gland swelling in HIV diffuse infiltrative CD8 lymphocytosis syndrome
1Division of Oral and Maxillofacial Surgery, Columbia University School of Dental and Oral Surgery and Columbia Presbyterian Medical Center, New York, NY 10032, USA.
Abstract:
HIV can affect salivary gland tissue. Parotid swellings have been observed in a subset of patients who are HIV-positive; the swellings are the result of a condition that has been termed diffuse infiltrative CD8 lymphocytosis syndrome. Initially the glandular enlargement results from a massive CD8 cell lymphoproliferation, but with time lymphoepithelial cysts become manifest. Two case reports are presented to illustrate this progression of diffuse infiltrative CD8 lymphocytosis.