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Nutritional amblyopia

S Lessell1

  • 1Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA.

Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
|June 11, 1998
PubMed
Summary
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Nutritional amblyopia presents uniquely, differing from typical cases. Factors like protein deficiency, not just vitamins, may cause this vision loss.

Area of Science:

  • Ophthalmology
  • Nutritional Science
  • Public Health

Background:

  • Nutritional amblyopia is a vision impairment linked to malnutrition.
  • Historical cases from World War II prisoners and Cuban embargo provide insights.

Purpose of the Study:

  • To review and characterize nutritional amblyopia.
  • To explore its pathogenesis and contributing factors.

Main Methods:

  • Literature review of published cases.
  • Analysis of amblyopia in malnourished populations (WWII prisoners, Cuban embargo).

Main Results:

  • Nutritional amblyopia exhibits atypical features: early corneal changes (keratopathy), swift vision loss, frequent hearing impairment, and peripapillary retinopathy.

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  • No single cause identified; genetic factors appear minimal.
  • Vitamin deficiency may not be the primary driver.

    • Conclusions:

    • Protein deficiency, antioxidant deficiency, physical labor, and smoking are potential contributors to nutritional amblyopia.
    • The disease's presentation can vary significantly from conventional understanding.